Qalandar is a story of a girl's firm belief in her God and His decisions while the rest of the world continues to hurt, defame and challenge her. Dur-e-Adan is a young and innocent girl who has grown up under the care of her uncle and aunt. Despite being an orphan at an early age, Dur-e-Adan doesn't complain about her challenges and difficulties. On the contrary, Tabriz is a handsome young man who aspires to achieve great things in life. Living in the same locality, Tabriz's parents find Dur-e-Adan suitable for him as a life partner. However, Tabriz's life takes a surprising turn when Sumbul hailing from a wealthy family falls in love with him. In efforts to secure his future financially, Tabriz forgets the gift that he has been bestowed in the form of Dur-e-Adan for this world and hereafter. Soon, Tabriz's half-heartedness and conflicting loyalties in the form of greed begins to reflect in his relationship with Dur-e-Adan. Amidst all the atrocities faced by Dur-e-Adan will she continue to be patient with those around her? Will Tabriz realize the respect and love that Dur-e-Adan deserves or will he continue to hurt her? Will Tabriz be able to mend his relationship with Dur-e-Adan?