Based on the 1979 comics and movie MANG KEPWENG, played by the legendary Chiquito, MANG KEPWENG RETURNS tells the story of the albularyo's son and his adventures with the magical bandanna. When Mang Kepweng died because of mysterious circumstances, buried with him was the secret that besides his son Zacharias (James Blanco), he had another son, Kiefer (Vhong Navarro), heir to the magic bandanna that has the power to cure any illness. Because of this, Mang Kepweng's old nemesis, Ingkong Kapiz (Pen Medina) returns to spread darkness and destroy Kiefer. With help from his mother, Aling Milagros (Jaclyn Jose) and Princess Alisandra (Jackie Rice)'s magic powers, Kiefer uses his newfound powers to save the world against evil as the new Mang Kepweng.